Prague (präg) The capital and largest city of the Czech Republic, in the western part of the country on the Vltava River. Known since the 9th century, it was a leading cultural and commercial center by the 14th century and came under Habsburg rule in 1526. Prague was the capital of Czechoslovakia from the country’s formation in 1918 until its dissolution in 1993.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.Prague (pr???) n (Placename) the capital and largest city of the Czech Republic, on the Vltava River: a rich commercial centre during the Middle Ages; site of Charles University (1348) and a technical university (1707); scene of defenestrations (1419 and 1618) that contributed to the outbreak of the Hussite Wars and the Thirty Years’ War respectively. Pop: 1 164 000 (2005 est). Czech name: Praha Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014Prague (pr?g) n. the capital of the Czech Republic, in the W central part, on the Vltava: formerly the capital of Czechoslovakia. 1,215,000. Czech, Pra?ha (?pr? h?) Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.