lym·pho·ma (l?m-f??m?)n. pl. lym·pho·ma·ta (-m?-t?) or lym·pho·mas 1. Any of various malignant tumors that arise from the lymphocytic cells of the immune system.2. Any of various cancers characterized by the development of such tumors, especially Hodgkin lymphoma and non-Hodgkin lymphoma.lym·pho?ma·toid?, lym·pho?ma·tous (-t?s) adj.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.lymphoma (l?m?f??m?) n, pl -mata (-m?t?) or -mas (Pathology) any form of cancer of the lymph nodes. Also called: lymphosarcoma lym?phomatous, lym?phoma?toid adjCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014lym?pho?ma (l?m?fo? m?) n., pl. -mas, -ma?ta (-m? t?) a tumor arising from any of the cellular elements of lymph nodes. [1870?75] lym?pho?ma?toid`, adj. Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.lymphomaa growth of lymphoid tissue that is commonly cancerous and typically enlarges the lymph nodes.See also: Cancer-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.