tsim·mes or tzim·mes (ts?m??s)n.1. A stew of vegetables or fruits cooked slowly over very low heat.2. Informal A state of confusion.[Yiddish tsimes : Middle High German ze, zuo, to, for (from Old High German; see de- in Indo-European roots) + Middle High German imbiz, light meal (from Old High German, from enbizzan, to eat : in, in; see en in Indo-European roots + b?zan, bizzan, to bite; see bheid- in Indo-European roots).]American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.tzim?mes or tsim?mes (?ts?m ?s) n. 1. a casserole or stew of vegetables, fruit, and sometimes meat. 2. Slang. fuss; uproar; hullabaloo. [1890?95;