tzetze fly (?ts?ts?) n (Animals) a variant spelling of tsetse flyCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014tset?se (or tzet?ze) fly` (?ts?t si, ?t?t-, ?tsi tsi, ?ti-) n. any of several bloodsucking African flies of the genus Glossina, including some that are vectors of trypanosomes that cause sleeping sickness and other diseases. Also called tset?se.[1860?65;