is·che·mi·a (?-sk??m?-?)n. A decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels.[New Latin ischaemia, from Greek iskhaimos, a stopping of the blood : iskhein, to keep back; see segh- in Indo-European roots + haima, blood.]i·sche?mic adj.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.is?che?mi?a (??ski mi ?) n. local deficiency of blood supply produced by vasoconstriction or local obstacles to the arterial flow. [1855?60;