San·ti·a·go (s?n?t?-ä?g?, sän?-)1. also São Tia·go (souN t?-ä?go?o, tyä?go?o) An island of southern Cape Verde in the northern Atlantic Ocean. It is the largest island in the group and the site of the capital, Praia.2. The capital and largest city of Chile, in the central part of the country east-southeast of Valparaiso. On a plain in the foothills of the Andes, it was founded in 1541.3. also Santiago de los Ca·bal·le·ros (d?? l?s kä?b?l-y?r??z, d? l?s kä?vä-y??r?s) A city of northern Dominican Republic northwest of Santo Domingo. Settled c. 1500, it is a transportation hub in a fertile agricultural region.4. also Santiago de Com·pos·te·la (d? k?m?p?-st?l??, th? k?m?p?s-t??lä) A city of northwest Spain south-southwest of La Coruña. The city grew around a shrine housing the reputed tomb of Saint James the Great (discovered in the ninth century) and has long been a pilgrimage center.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.Santiago de Compostela (Spanish de k?mp?s?tela) n (Placename) a city in NW Spain: place of pilgrimage since the 9th century and the most visited (after Jerusalem and Rome) in the Middle Ages; cathedral built over the tomb of the apostle St James. Pop: 92 339 (2003 est). Latin name: Campus Stellae Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014