ge·nome (j??n?m?)n.1. The total genetic content contained in a haploid set of chromosomes in eukaryotes, in a single chromosome in bacteria or archaea, or in the DNA or RNA of viruses.2. An organism’s genetic material.[gen(e) + -ome.]ge·no?mic (-n??m?k) adj.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.genome (?d?i?n??m) or genomn1. (Genetics) the full complement of genetic material within an organism2. (Biology) all the genes comprising a haploid set of chromosomes[C20: from German Genom, from Gen gene + (chromos)ome] genomic adjCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014ge?nome (?d?i no?m) n. a full haploid set of chromosomes with all its genes; the total genetic constitution of a cell or organism. [1925?30;