gly·co·sy·la·tion (gl??k?-s?-l??sh?n)n. The addition of saccharides to proteins or lipids to form a glycoprotein or glycolipid.[glycose, a monosaccharide (variant of glucose) + -yl + -ation.]gly·co?sy·late? v.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.glycosylation (??la?k??s??le???n) n (Biochemistry) the process by which sugars are chemically attached to proteins to form glycoproteins[from glycosyl radical derived from glycose + -ation]Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014