na·ga·na also n’ga·na (n?-gä?n?)n. An often fatal disease of domestic animals in sub-Saharan Africa, caused by various trypanosomes transmitted by tsetse flies and characterized by fever, anemia, and emaciation.[Zulu -nakane.]American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.nagana (n?????n?) n (Veterinary Science) a disease of domesticated animals of central and southern Africa, caused by parasitic protozoa of the genus Trypanosoma transmitted by tsetse flies[from Zulu u-nakane]Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014na?ga?na (n??g? n?) n. a disease of livestock and other animals, widespread in parts of Africa, caused by several species of trypanosomes and transmitted by a variety of tsetse fly. [1890?95;