gran·u·lo·ma (gr?n?y?-l??m?)n. pl. gran·u·lo·mas or gran·u·lo·ma·ta (-m?-t?) Any of various nodular masses of granulocytic monocytes and other immune cells, including macrophages and eosinophils, that aggregate in response to a chronic infection, such as tuberculosis, or other inflammatory process.gran?u·lo?ma·tous (-m?-t?s) adj.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.granuloma (??rænj??l??m?) n, pl -mas or -mata (-m?t?) (Pathology) a tumour composed of granulation tissue produced in response to chronic infection, inflammation, a foreign body, or to unknown causes granulomatous adjCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014gran?u?lo?ma (?græn y??lo? m?) n., pl. -mas, -ma?ta (-m? t?) an inflammatory tumor or growth composed of granulation tissue. [1860?65] gran`u?lom?a?tous (-?l?m ? t?s) adj. Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.