Se·ville (s?-v?l?) A city of southwest Spain on the Guadalquivir River north-northeast of Cádiz. An important settlement under the Romans, Vandals, and Visigoths, it was conquered by the Moors in ad 712 and later taken by Ferdinand III of Castile, who made it his royal residence in 1248. The city especially prospered after the discovery of the New World and served as the chief port of colonial trade until the early 1700s.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.Seville (s??v?l) n (Placename) a port in SW Spain, on the Guadalquivir River: chief town of S Spain under the Vandals and Visigoths (5th?8th centuries); centre of Spanish colonial trade (16th?17th centuries); tourist centre. Pop: 709 975 (2003 est). Ancient name: Hispalis Spanish name: Sevilla Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014Se?ville (s??v?l) n. a port in SW Spain, on the Guadalquivir River. 668,356. Spanish, Se?vi?lla (s??vi ly?) Se?vil?lian (-y?n) adj., n. Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.