Is·fa·han (?s?f?-hän?) See Esfahan.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.Isfahan (??sf??h??n) or E?fah?nn (Placename) a city in central Iran: the second largest city in the country; capital of Persia in the 11th century and from 1598 to 1722. Pop: 1 547 000 (2005 est). Ancient name: Aspadana Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014Is?fa?han (??s f??h?n) also Ispahan n. a city in central Iran: the capital of Persia from the 16th into the 18th century. 986,753. Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.