graph·eme (gr?f??m?)n.1. A letter of an alphabet.2. All of the letters and letter combinations that represent a phoneme, as f, ph, and gh for the phoneme /f/.[graph + -eme.]gra·phe?mic (gr?-f??m?k) adj.gra·phe?mi·cal·ly adv.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.grapheme (??ræfi?m) n (Linguistics) linguistics one of a set of orthographic symbols (letters or combinations of letters) in a given language that serve to distinguish one word from another and usually correspond to or represent phonemes, e.g. the f in fun, the ph in phantom, and the gh in laugh[C20: from Greek graph?ma a letter] gra?phemic adj gra?phemically advCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014graph?eme (?græf im) n. 1. a minimal unit of a writing system. 2. a unit of a writing system consisting of all the written symbols or sequences of written symbols that are used to represent a single phoneme. [1935?40;