gramme (gr?m)n. Chiefly British Variant of gram1.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.gramme (?ræm) n (Units) a variant spelling of gram1Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014gram1 (græm) n. a metric unit of mass or weight equal to 15.432 grains; 1/1000 of a kilogram. Abbr.: g, gr, gr. Also, esp. Brit., gramme. [1790?1800;