zo·o·spore (z???-spôr?)n. A motile flagellated asexually produced spore, as of certain algae, oomycetes, and fungi.zo?o·spor?ic adj.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.