pre·puce (pr??pyo?os?)n.1. See foreskin.2. A loose fold of skin covering the glans clitoridis.[Middle English, from Old French, from Latin praep?tium : possibly prae-, pre- + *p?tos, penis.]pre·pu?tial (-pyo?o?sh?l) adj.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.