nerve centern.1. A group of closely connected nerve cells that perform a specific function.2. A source of power or control: Our Boston office is the nerve center of the corporation.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.nerve? cen`ter n. 1. a group of nerves that act together to perform a function. 2. a source of information or activity; control center. [1865?70] Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.