Nicholas of Cu·sa (kyo?o?z?, -s?) 1401-1464. German prelate, scientist, and Neoplatonist philosopher who emphasized the incompleteness of human knowledge of God and nature.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.Nicholas of Cusa (?kju?z?) n (Biography) 1401?64, German cardinal, philosopher, and mathematician: anticipated Copernicus in asserting that the earth revolves around the sunCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014