multicentric (?m?lt??s?ntr?k) adj1. (Medicine) originating in or involving several parts of the body or of an organ2. (Biology) (of a chromosome) having more than one centromereCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014