Mrs. (m?s??z)n. pl. Mmes. (m?-däm?, -d?m?) 1. Used as a courtesy title for a married, widowed, or divorced woman before her own surname or full name: Mrs. Doe; Mrs. Jane Doe. See Usage Note at miss2.2. Used as a courtesy title for a married or widowed woman before the surname or full name of her husband: Mrs. Doe; Mrs. John Doe.3. Used in informal titles for a married woman to indicate the epitomizing of an attribute or activity: Mrs. Wonderful; Mrs. Organization.[Abbreviation of mistress.]American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.Mrs. – Originally, Mrs. was a shortened version of mistress, a word that used to mean “wife”; Mrs. cannot be written out.See also related terms for mistress.Farlex Trivia Dictionary. © 2012 Farlex, Inc. All rights reserved.