co·li·tis (k?-l??t?s)n. Inflammation of the colon. Also called colonitis.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.colitis (k??la?t?s; k?-) or colonitisn (Pathology) inflammation of the colon colitic adjCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014co?li?tis (k??la? t?s, ko?-) n. inflammation of the colon. [1855?60] Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.colitisInflammation of the large intestine or colon. It may result from a viral or bacterial infection, causing pain and severe diarrhea.Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited