-cephalysuff. A specified condition of the head: microcephaly.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.ce?phal?ic (s??fæl ?k) adj. 1. of or pertaining to the head. 2. situated or directed toward the head. [1590?1600;