B2B abbreviation for (Commerce) business to business: denoting trade between commercial organizations rather than between businesses and private customers. Compare B2C, B2E Collins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014B2B or B-to-B (?bi t??bi) business-to-business: B2B Web sites. [1990?95] Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.