i·so·la·tion (??s?-l??sh?n)n.1. The act of isolating: ordered the isolation of the sick patients.2. The quality or condition of being isolated: isolation on a desert island.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.isolation (?a?s??le???n) n1. the act of isolating or the condition of being isolated2. (Government, Politics & Diplomacy) (of a country, party, etc) nonparticipation in or withdrawal from international politics3. (Medicine) med a. social separation of a person who has or is suspected of having a contagious disease. Compare quarantineb. (as modifier): an isolation hospital. 4. (Sociology) sociol a lack of contact between persons, groups, or whole societies5. (Psychology) social psychol the failure of an individual to maintain contact with others or genuine communication where interaction with others persists6. in isolation without regard to context, similar matters, etcCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014