de·ox·y·cor·ti·cos·ter·one (d?-?k?s?-kôr?t?-k?s?t?-r?n?)n. A steroid hormone, C21H30O3, secreted by the adrenal cortex or produced synthetically and formerly used to treat adrenal insufficiency.American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.deoxycorticosterone (di???ks??k??t?k???st??r??n) or deoxycortonen (Biochemistry) a corticosteroid hormone important in maintaining sodium and water balance in the bodyCollins English Dictionary ? Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014de?ox?y?cor?ti?cos?ter?one (di??k s??k?r t??k?s t??ro?n, -?ko? st??ro?n) n. a steroid hormone, C21H30O3, secreted by the adrenal cortex, related to corticosterone, and involved in water and electrolyte balance. Random House Kernerman Webster’s College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.